| Team | W | L | GB | % |
| NY Yankee | 61 | 25 | 0.0 | .709 |
| Boston | 47 | 40 | 14.5 | .540 |
| Tampa Bay | 46 | 40 | 15.0 | .535 |
| Toronto | 45 | 42 | 16.5 | .517 |
| Baltimore | 43 | 44 | 18.5 | .494 |
















| Team | W | L | GB | % |
| NY Yankee | 61 | 25 | 0.0 | .709 |
| Boston | 47 | 40 | 14.5 | .540 |
| Tampa Bay | 46 | 40 | 15.0 | .535 |
| Toronto | 45 | 42 | 16.5 | .517 |
| Baltimore | 43 | 44 | 18.5 | .494 |
| Team | W | L | GB | % |
| Minnesota | 48 | 40 | 0.0 | .545 |
| Cleveland | 42 | 42 | 4.0 | .500 |
| Chi White Sox | 41 | 44 | 5.5 | .482 |
| Detroit | 36 | 51 | 11.5 | .414 |
| Kansas City | 34 | 52 | 13.0 | .395 |
| Team | W | L | GB | % |
| Houston | 56 | 29 | 0.0 | .659 |
| Seattle | 45 | 42 | 12.0 | .517 |
| Texas | 40 | 44 | 15.5 | .476 |
| LA Angels | 38 | 49 | 19.0 | .437 |
| Oakland | 29 | 59 | 28.5 | .330 |
| Team | W | L | GB | % |
| NY Mets | 54 | 33 | 0.0 | .621 |
| Atlanta | 52 | 36 | 2.5 | .591 |
| Philadelphia | 46 | 41 | 8.0 | .529 |
| Miami | 41 | 44 | 12.0 | .482 |
| Washington | 30 | 58 | 24.5 | .341 |
| Team | W | L | GB | % |
| Milwaukee | 48 | 39 | 0.0 | .552 |
| St. Louis | 47 | 42 | 2.0 | .528 |
| Pittsburgh | 37 | 50 | 11.0 | .425 |
| Chi Cubs | 34 | 52 | 13.5 | .395 |
| Cincinnati | 32 | 54 | 15.5 | .372 |
| Team | W | L | GB | % |
| LA Dodgers | 56 | 29 | 0.0 | .659 |
| San Diego | 50 | 38 | 7.5 | .568 |
| San Francisco | 43 | 41 | 12.5 | .512 |
| Arizona | 38 | 48 | 18.5 | .442 |
| Colorado | 38 | 49 | 19.0 | .437 |
| 2021 Season Key Dates | | |
| Regular Season | April 1 – October 3 |
| MLB Draft | July 11-13 |
| All-Star Game | July 13 |
| Trade Deadline | July 30 |
| Playoffs Begin | October 5 |
| World Series | October 26 |